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A luxurious serum with SYN-AKE peptide and rose water
A silky, completely non-greasy serum for mature skin that needs hydration and a smoother, more relaxed appearance. SYN-AKE peptide, inspired by a snake peptide, helps smooth expression lines while Damask rose water with oat and argan oils moisturises and nourishes the skin. We make it in our own production facility in Trenčín.
4.9 out of 529 reviews
SYN-AKEa peptide for expression lines
30 mlnon-greasy serum
Trenčínour own production
Who it is for
For mature skin, including skin prone to imperfections
You have mature skin and want it to look smoother, firmer and more rested.
You enjoy a lightweight, non-greasy texture that works well under make-up too.
Your skin is prone to imperfections and needs its moisture and oil levels balanced.
Do not use on irritated or sensitive skin or if you are sensitive to any ingredient. Not suitable for children.
Before first use, test the serum on a small area first, such as your forearm, and wait 24 to 48 hours.
Benefits
What it does for your skin
SYN-AKE peptide helps smooth expression lines and leaves the skin looking more relaxed.
It supports the production of elastin and collagen, firming and rejuvenating the skin.
It helps balance moisture and oil levels and restore a healthy skin barrier.
It moisturises and leaves the skin soft, supple and nourished.
It is completely non-greasy and silky, absorbing without leaving a film.
Your skin looks fresher, more rested and brighter.
Applied under cream, it enhances the cream's effect.
The natural oils, rose hydrolate and active ingredients are rich in mineral nutrients, vitamins and fatty acids, giving the skin a luxurious feel.
Key ingredients: SYN-AKE peptide, Damask rose water, oat oil and argan oil
SYN-AKE peptide
Dipeptide Diaminobutyroyl Benzylamide Diacetate
a neuropeptide developed based on the structure of a peptide from the temple viper
moisturises the skin and gives it a pleasant fragrance
smooths and firms, bringing balance to the skin
great for mature and sensitive skin
Oat lipid oil
Avena Sativa Kernel Oil
a high concentration of ceramides
omega 3 and 6 fatty acids
long-lasting hydration
leaves the skin soft, supple and nourished
Argan oil
Argania Spinosa Oil
organic oil rich in vitamin E and fatty acids
strongly regenerating and softening
restores vitality to mature skin too
Squalane
Squalane
a natural moisturising ingredient that locks water into the skin
strengthens the natural lipid barrier
prevents excessive water evaporation
smooths, softens and restores radiance to the skin
Other active ingredients
BoswelliaBoswellia Serrata Resin ExtractViaPure Boswellia for anti-ageing care: soothes and firms the skin, inhibits elastase and improves skin barrier function.
ResveratrolResveratrolA polyphenol that plants use to defend themselves against pests and fungi; some scientists call it an elixir of youth.
Echium oil and beta NMNEchium Plantagineum Seed, Nicotinamide MononucleotideEchium oil is great for dry skin and helps smooth fine lines; NMN plays a role in cellular energy production.
Pentylene glycolPentylene GlycolHydrates without drying, binds water and helps deliver active ingredients deeper into the skin, which then looks brighter.
Essential oilsBoswellia Carterii Gum Oil, Helichrysum Italicum Flower Oil, Tanacetum Annuum Flower Oil, Citrus JunosFrankincense soothes and renews the skin, helichrysum rejuvenates, blue tansy soothes and yuzu brightens and tones.
Siligel and lysolecithinXanthan Gum, Sclerotium Gum, Pullulan, Lecithin, LysolecithinA natural gelling ingredient gives the serum its silky texture, while lysolecithin increases the skin's affinity for water.
How to use
Three steps morning and evening
1Gently cleanse and pat your skin dry morning and evening.
2Apply a thin layer of serum and gently massage it in.
3Pat into your face and neck, let it absorb and follow with cream.
What to expect
How your skin may feel after the first use
After applicationThe serum spreads easily and absorbs into the skin. It does not leave the skin greasy, and you can barely feel it on your face.
During the daySkin feels supple and pleasantly nourished. Customers wear it under make-up too.
With regular useTogether with toner and cream, it forms a routine you enjoy returning to. Everyone's skin is different.
“SI KRÁSNA is a truly luxurious serum. Like the cream, it spreads easily and does not leave the skin greasy. … Together with the cream, it makes a great duo.”
The people behind it
A family business, with our own production in Trenčín
I wanted a serum that would feel silky and completely non-greasy on the skin, while delivering SYN-AKE peptide, rose water and oat and argan oils. Under SI KRÁSNA cream, morning and evening.
ErikaErika Bundalováproduct developer & co-founder of Panakeia
Alongside Erika: Albi (marketing), Maťka (help with choosing products) and Patrik (tinctures).
Storage: at room temperature, away from heat sources and direct sunlight
Warnings: For external use only. Avoid contact with the eyes and mucous membranes. Do not use on irritated or sensitive skin, or if you are sensitive to any ingredient. Not suitable for children. Keep out of the reach of children.
Responsible person: PANAKEIA SK s. r. o., Žabinská 2081/2, 911 05 Trenčín, Slovakia · panakeia@panakeia.sk
Questions
What you ask most often
What is SYN-AKE?
A peptide (Dipeptide Diaminobutyroyl Benzylamide Diacetate) developed based on the structure of a peptide from the temple viper. It relaxes tiny muscle contractions, helping smooth expression lines. It is vegan; no snakes were harmed.
Is the serum greasy?
No. It is completely non-greasy and silky, even though it contains oils. Customers say it absorbs straight away, they can barely feel it on their face and it works well under make-up too.
How should I combine it with cream?
Apply the serum first, let it absorb and then use cream. The serum provides active ingredients; the cream seals them in. According to reviews, customers find SI KRÁSNA serum and cream make a great duo.
Can I use it morning and evening?
Yes, morning and evening on clean skin. Some customers wear it in the morning and reach for Kopaničiarska žehlička in the evening.
Is it suitable for the eye area too?
One customer also uses it around her eyes and says it does not sting them. Do not apply it in the eyes, and avoid contact with mucous membranes.
Which skin types is it suitable for?
For mature skin prone to imperfections that needs hydration and renewal. Do not use on irritated or sensitive skin or if you are sensitive to any ingredient.
How do I do a tolerance test?
Before first use, apply a small amount to a small area, such as your forearm or behind your ear, and wait 24 to 48 hours.
How long does 30 ml last?
With daily use, about two to three months. The small pack is handy for travel too.
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4,9
The average product rating is 4,9 out of 5 stars.29 ratings
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List of ratings
3Customer
The product rating is 3 out of 5 stars.
06/09/2026
- Nepríjemná vôňa
- Pomalé vstrebávanie
5Customer
The product rating is 5 out of 5 stars.
03/08/2026
Super krém a sérum ❤️
5Customer
The product rating is 5 out of 5 stars.
06/05/2026
Serum Si krasna,tak ako aj krem som si kupila uz viackrat.Je dobre roztieratelne,nemasti plet,nestipu ma po nom oci,kedze ja velmi nemam rada ocne kremy,pouzivam ho aj na ocne okolie.Tiez nema silnu vonu a skvelo sa doplna spolu s kremom Si krasna.Vrelo odporucam,urcite nesklame.
5Customer
The product rating is 5 out of 5 stars.
08/12/2025
Šermu sa krásne vstrekne do pokožky zatiaľ používam krátko
5Customer
The product rating is 5 out of 5 stars.
18/10/2025
- Ziadna
S liftingovym serom Si krasna som velmi spokojna.Mam ho uz druhykrat.Je jemne,nemastí pokozku,tiez ho na tvari ani necitite,ma nevtieravu vonu,velmi dobre sa rozotiera.Pokozka zostane jemna a spolu s pletovou vodou alebo tonikom a kremom,vytvori velmi dobry efekt.Je dolezite pravidelne pouzivanie a aj pravidelne cistenie tvare .Za mna spolu s kremom TOP produkt.
5Customer
The product rating is 5 out of 5 stars.
09/09/2025
Si krasna,je naozaj luxusne serum.Tak ako kremik,sa tiez dobre roztiera,neostava plet mastna.Pouzivam ho rano,pretoze na noc si davam serum Kopaniciarsku zehlicku,ktore je tiez vynikajuce,pozivala som ho predtym rano aj vecer.Splna vsetky moje ocakavania,citim sa velmi pohodlne,lebo ma pocas dna plet nesvrbi od suchosti,nemusim mysliet na to,ze sa musim pocas dna znovu natriet.Som velmi spokojna,nelutujem,ze som si kupila prave toto serum.Tiez vhodne svojim balenim aj na cestovanie.Spolu s kremikom tvoria super duo.Zlozenie je tiez kvalitne,za mna urcite odporucam vyskusat.
5Customer
The product rating is 5 out of 5 stars.
05/08/2025
Skvelé sérum, som s ním veľmi spokojná. Asi najviac z produktov, ktoré som vyskúšala.
4Customer
The product rating is 4 out of 5 stars.
23/07/2025
Nevidela som na svojej pleti žiadnu pozitívnu zmenu pri používaní tohto sera a to som nakúpila viac produktov Panakeia ako mi bolo odporučené a dodržala som proces od čistenia až po sérum....
5Customer
The product rating is 5 out of 5 stars.
30/06/2025
Jemnejšia pleť, dobrý pocit.
5Customer
The product rating is 5 out of 5 stars.
28/06/2025
Luxus v tejto ampulke. Uz z názvu je jasne čo po používaní môžeme cakat. Serum je nemastne, vhodne aj pod makeup. U mna velka spokojnosť.
5Customer
The product rating is 5 out of 5 stars.
21/06/2025
+ Zatiaľ ešte som to použila asi 2x takže celkom hodnotiť neviem ,ale pleť je hladsia a menej mastná,len by som uvítala formulku koľko krát do týždňa môžem používať sérum,alebo masku
5Customer
The product rating is 5 out of 5 stars.
26/11/2024
+ So sérom som spokojná, vyhovuje mojej pleti.
5Customer
The product rating is 5 out of 5 stars.
22/03/2024
Ľahko sa nanáša a rýchlo vpije do pokožky.
5Customer
The product rating is 5 out of 5 stars.
25/07/2023
+ Kvalita
5Customer
The product rating is 5 out of 5 stars.
18/04/2023
+ Ak by bolo v ponuke litrove balenie, nevaham a kupujem
5Customer
The product rating is 5 out of 5 stars.
04/04/2023
+ Používam pravidelne, a som veľmi spokojná.
5Customer
The product rating is 5 out of 5 stars.
11/01/2023
+ Vyborne hydratuje, vypina, rychlo sa vstrebava
5Customer
The product rating is 5 out of 5 stars.
29/11/2022
+ Zdá sa mi že pleť je hladšia, nepôsobí mdlym dojmom
5Customer
The product rating is 5 out of 5 stars.
14/05/2022
+ Pleť mám krásne sviežu, hebkú a vláčnu.Vhodné na suchú pleť.Určite si ho ešte objednám.Len odporúčam
- Žiadne
Sérum je skvelé,omladzuje a zvláčňuje pokožku. Ja mám suchú zrelú pleť, u mňa veľká spokojnosť Cena zodpovedá kvalite
5Customer
The product rating is 5 out of 5 stars.
01/01/1970
zatial maximálna spokojnosť, sérum sa pekne vpije do pokožky a tá je potom taká príjemne akurátna, vyživená (mám suchú pokožku)